\n
\n\t\u0130ngiliz bilim insanlar\u0131, kanser tedavisinde \u00e7\u0131\u011f\u0131r a\u00e7acak devrim niteli\u011finde bir a\u015f\u0131 geli\u015ftirdi. Oxford \u00dcniversitesi ile ila\u00e7 firmas\u0131 Moderna ortakl\u0131\u011f\u0131nda y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmada, \u00f6zellikle genetik olarak y\u00fcksek kanser riski ta\u015f\u0131yan bireylerde ba\u011f\u0131rsak ve yumurtal\u0131k kanserinin \u00f6nlenmesi ama\u00e7lan\u0131yor.<\/p>\n
\n\tCovid-19 a\u015f\u0131lar\u0131nda ba\u015far\u0131s\u0131n\u0131 kan\u0131tlayan mRNA teknolojisinin ilk kez kanseri \u00f6nleme amac\u0131yla kullan\u0131laca\u011f\u0131 bu tarihi deneme i\u00e7in ilk hasta uygulamalar\u0131n\u0131n bu yaz ba\u015flamas\u0131 planlan\u0131yor.<\/p>\n
\n\tHedefte gizli tehlike “Lynch Sendromu” var<\/h2>\n
\n\tGeli\u015ftirilen a\u015f\u0131, \u00f6ncelikli olarak “Lynch sendromu” ad\u0131 verilen kal\u0131tsal bir rahats\u0131zl\u0131\u011fa sahip ki\u015fileri korumay\u0131 hedefliyor. \u0130ngiltere\u2019de her 300 ki\u015fiden birinde g\u00f6r\u00fclen bu genetik durum, DNA\u2019y\u0131 onarmakla g\u00f6revli genlerin hasarl\u0131 olmas\u0131ndan kaynaklan\u0131yor.<\/p>\n
\n\tBu sendroma sahip bireylerin hayat boyu ba\u011f\u0131rsak kanserine yakalanma riski yakla\u015f\u0131k y\u00fczde 80 artarken; yumurtal\u0131k, rahim, mide ve pankreas gibi di\u011fer kanser t\u00fcrlerine yakalanma ihtimalleri de \u00e7ok y\u00fcksek seyrediyor. \u00dcstelik bu geni ta\u015f\u0131yan tahmini 175 bin ki\u015fiden yaln\u0131zca y\u00fczde 5’i durumun fark\u0131nda. A\u015f\u0131, bu ki\u015filerin v\u00fccudunda kanser h\u00fccreleri hen\u00fcz olu\u015fmadan, “kanser \u00f6ncesi” evredeki anormallikleri tespit etmek \u00fczere tasarland\u0131.<\/p>\n
\n\tBa\u011f\u0131\u015f\u0131kl\u0131k sistemine “kanserle m\u00fccadele k\u0131lavuzu”<\/h2>\n
\n\tmRNA teknolojisiyle \u00fcretilen a\u015f\u0131, geleneksel a\u015f\u0131lardan farkl\u0131 bir y\u00f6ntemle \u00e7al\u0131\u015f\u0131yor. V\u00fccuda do\u011frudan zay\u0131flat\u0131lm\u0131\u015f vir\u00fcs vermek yerine, h\u00fccrelere ba\u011f\u0131\u015f\u0131kl\u0131k yan\u0131t\u0131 olu\u015fturmas\u0131 i\u00e7in genetik talimatlar iletiyor. Uzmanlar, a\u015f\u0131n\u0131n adeta bir “kullan\u0131m k\u0131lavuzu” gibi hareket ederek ba\u011f\u0131\u015f\u0131kl\u0131k sistemini e\u011fitti\u011fini belirtiyor.<\/p>\n
\n\tBu sayede savunma mekanizmas\u0131, Lynch sendromunun tetikledi\u011fi h\u00fccre mutasyonlar\u0131n\u0131 hen\u00fcz kansere d\u00f6n\u00fc\u015fmeden fark edip yok edecek. A\u015f\u0131n\u0131n zaman i\u00e7inde g\u00fcc\u00fcn\u00fc korumas\u0131 i\u00e7in belirli aral\u0131klarla hat\u0131rlatma dozlar\u0131n\u0131n yap\u0131lmas\u0131 gerekebilecek.<\/p>\n
\n\tGelecekte t\u00fcm kanser t\u00fcrleri i\u00e7in umut olabilir<\/h2>\n
\n\tBu yaz ba\u015flat\u0131lacak olan ilk a\u015famada, hastalar \u00fczerinde en do\u011fru dozaj belirlenecek ve a\u015f\u0131n\u0131n g\u00fcvenli\u011fi test edilecek. \u00c7al\u0131\u015fman\u0131n \u00e7ok merkezli ikinci a\u015famas\u0131n\u0131n ise 2027 y\u0131l\u0131nda geni\u015fletilmesi \u00f6ng\u00f6r\u00fcl\u00fcyor. Bilim insanlar\u0131, a\u015f\u0131n\u0131n sadece Lynch sendromlu hastalar\u0131 korumakla kalmayaca\u011f\u0131n\u0131, ayn\u0131 zamanda daha \u00f6nce kanser atlatm\u0131\u015f ki\u015filerin ikinci bir kansere yakalanmas\u0131n\u0131 da \u00f6nleyebilece\u011fini vurguluyor.<\/p>\n
\n\tAra\u015ft\u0131rma ekibi, bu denemeden elde edilecek ba\u015far\u0131 ve ba\u011f\u0131\u015f\u0131kl\u0131k verilerinin, gelecekte genetik ba\u011flam\u0131 olmayan di\u011fer yayg\u0131n kanser t\u00fcrlerine kar\u015f\u0131 da a\u015f\u0131 geli\u015ftirilmesinin \u00f6n\u00fcn\u00fc a\u00e7aca\u011f\u0131n\u0131 ifade ediyor.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"
\u0130ngiliz bilim insanlar\u0131, kanser tedavisinde \u00e7\u0131\u011f\u0131r a\u00e7acak devrim niteli\u011finde bir a\u015f\u0131 geli\u015ftirdi. Oxford \u00dcniversitesi ile ila\u00e7 firmas\u0131 Moderna ortakl\u0131\u011f\u0131nda y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmada, \u00f6zellikle genetik olarak y\u00fcksek kanser riski ta\u015f\u0131yan bireylerde ba\u011f\u0131rsak ve yumurtal\u0131k kanserinin \u00f6nlenmesi ama\u00e7lan\u0131yor.
Covid-19 a\u015f\u0131lar\u0131nda ba\u015far\u0131s\u0131n\u0131 kan\u0131tlayan mRNA teknolojisinin ilk kez kanseri \u00f6nleme amac\u0131yla kullan\u0131laca\u011f\u0131 bu tarihi deneme i\u00e7in ilk hasta […]<\/p>\n","protected":false},"author":1,"featured_media":41266,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[2],"tags":[],"class_list":["post-41265","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"yoast_head":"\n
Kansere kar\u015f\u0131 d\u00fcnyada bir ilk: Yeni mRNA a\u015f\u0131s\u0131 geli\u015ftirildi - Haber Kuzey<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kansere kar\u015f\u0131 d\u00fcnyada bir ilk: Yeni mRNA a\u015f\u0131s\u0131 geli\u015ftirildi - Haber Kuzey\" \/>\n<meta property=\"og:description\" content=\"
\u0130ngiliz bilim insanlar\u0131, kanser tedavisinde \u00e7\u0131\u011f\u0131r a\u00e7acak devrim niteli\u011finde bir a\u015f\u0131 geli\u015ftirdi. Oxford \u00dcniversitesi ile ila\u00e7 firmas\u0131 Moderna ortakl\u0131\u011f\u0131nda y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmada, \u00f6zellikle genetik olarak y\u00fcksek kanser riski ta\u015f\u0131yan bireylerde ba\u011f\u0131rsak ve yumurtal\u0131k kanserinin \u00f6nlenmesi ama\u00e7lan\u0131yor.
Covid-19 a\u015f\u0131lar\u0131nda ba\u015far\u0131s\u0131n\u0131 kan\u0131tlayan mRNA teknolojisinin ilk kez kanseri \u00f6nleme amac\u0131yla kullan\u0131laca\u011f\u0131 bu tarihi deneme i\u00e7in ilk hasta […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/\" \/>\n<meta property=\"og:site_name\" content=\"Haber Kuzey\" \/>\n<meta property=\"article:published_time\" content=\"2026-06-09T18:53:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trthaberstatic.cdn.wp.trt.com.tr\/resimler\/1954000\/kanser-1954769.jpg\" \/>\n<meta name=\"author\" content=\"haberkuzey\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"haberkuzey\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2026\\\/06\\\/09\\\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2026\\\/06\\\/09\\\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\\\/\"},\"author\":{\"name\":\"haberkuzey\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/#\\\/schema\\\/person\\\/3372109ec735f9333f4fa47ebb9605ca\"},\"headline\":\"Kansere kar\u015f\u0131 d\u00fcnyada bir ilk: Yeni mRNA a\u015f\u0131s\u0131 geli\u015ftirildi\",\"datePublished\":\"2026-06-09T18:53:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2026\\\/06\\\/09\\\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\\\/\"},\"wordCount\":455,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2026\\\/06\\\/09\\\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/haberkuzey.com\\\/wp-content\\\/uploads\\\/2026\\\/06\\\/kanser-1954769.jpg\",\"articleSection\":[\"D\u00fcnya\"],\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2026\\\/06\\\/09\\\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2026\\\/06\\\/09\\\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\\\/\",\"url\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2026\\\/06\\\/09\\\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\\\/\",\"name\":\"Kansere kar\u015f\u0131 d\u00fcnyada bir ilk: Yeni mRNA a\u015f\u0131s\u0131 geli\u015ftirildi - 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Haber Kuzey","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/","og_locale":"tr_TR","og_type":"article","og_title":"Kansere kar\u015f\u0131 d\u00fcnyada bir ilk: Yeni mRNA a\u015f\u0131s\u0131 geli\u015ftirildi - Haber Kuzey","og_description":"
\u0130ngiliz bilim insanlar\u0131, kanser tedavisinde \u00e7\u0131\u011f\u0131r a\u00e7acak devrim niteli\u011finde bir a\u015f\u0131 geli\u015ftirdi. Oxford \u00dcniversitesi ile ila\u00e7 firmas\u0131 Moderna ortakl\u0131\u011f\u0131nda y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmada, \u00f6zellikle genetik olarak y\u00fcksek kanser riski ta\u015f\u0131yan bireylerde ba\u011f\u0131rsak ve yumurtal\u0131k kanserinin \u00f6nlenmesi ama\u00e7lan\u0131yor.
Covid-19 a\u015f\u0131lar\u0131nda ba\u015far\u0131s\u0131n\u0131 kan\u0131tlayan mRNA teknolojisinin ilk kez kanseri \u00f6nleme amac\u0131yla kullan\u0131laca\u011f\u0131 bu tarihi deneme i\u00e7in ilk hasta […]","og_url":"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/","og_site_name":"Haber Kuzey","article_published_time":"2026-06-09T18:53:00+00:00","og_image":[{"url":"https:\/\/trthaberstatic.cdn.wp.trt.com.tr\/resimler\/1954000\/kanser-1954769.jpg","type":"","width":"","height":""}],"author":"haberkuzey","twitter_card":"summary_large_image","twitter_misc":{"Yazan:":"haberkuzey","Tahmini okuma s\u00fcresi":"2 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/#article","isPartOf":{"@id":"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/"},"author":{"name":"haberkuzey","@id":"https:\/\/haberkuzey.com\/#\/schema\/person\/3372109ec735f9333f4fa47ebb9605ca"},"headline":"Kansere kar\u015f\u0131 d\u00fcnyada bir ilk: Yeni mRNA a\u015f\u0131s\u0131 geli\u015ftirildi","datePublished":"2026-06-09T18:53:00+00:00","mainEntityOfPage":{"@id":"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/"},"wordCount":455,"commentCount":0,"image":{"@id":"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/#primaryimage"},"thumbnailUrl":"https:\/\/haberkuzey.com\/wp-content\/uploads\/2026\/06\/kanser-1954769.jpg","articleSection":["D\u00fcnya"],"inLanguage":"tr","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/","url":"https:\/\/haberkuzey.com\/index.php\/2026\/06\/09\/kansere-karsi-dunyada-bir-ilk-yeni-mrna-asisi-gelistirildi\/","name":"Kansere kar\u015f\u0131 d\u00fcnyada bir ilk: Yeni mRNA a\u015f\u0131s\u0131 geli\u015ftirildi - 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