{"id":31612,"date":"2025-11-12T04:30:00","date_gmt":"2025-11-12T02:30:00","guid":{"rendered":"https:\/\/haberkuzey.com\/index.php\/2025\/11\/12\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\/"},"modified":"2025-11-12T04:30:00","modified_gmt":"2025-11-12T02:30:00","slug":"bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti","status":"publish","type":"post","link":"https:\/\/haberkuzey.com\/index.php\/2025\/11\/12\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\/","title":{"rendered":"Bilim insanlar\u0131 yayg\u0131n bir kanser t\u00fcr\u00fcn\u00fcn viral nedenini ke\u015ffetti"},"content":{"rendered":"

<\/p>\n

\n


\n\tABD Ulusal Alerji ve Bula\u015f\u0131c\u0131 Hastal\u0131klar Enstit\u00fcs\u00fc\u2019nden (NIAID) imm\u00fcnolog Andrea Lisco liderli\u011findeki ara\u015ft\u0131rma ekibi, \u201cbeta-HPV\u201d olarak bilinen vir\u00fcs\u00fcn, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi zay\u0131flam\u0131\u015f bireylerde h\u00fccrelerin DNA\u2019s\u0131na yerle\u015ferek kanser geli\u015fimini tetikleyebildi\u011fini tespit etti.<\/p>\n


\n\t34 ya\u015f\u0131ndaki kad\u0131n\u0131n vakas\u0131 bilimsel d\u00f6n\u00fcm noktas\u0131 oldu<\/h2>\n


\n\tAra\u015ft\u0131rma, al\u0131n b\u00f6lgesinde kutan\u00f6z skuam\u00f6z h\u00fccreli karsinom (cSCC) ad\u0131 verilen bir t\u00fcr cilt kanseri geli\u015fen 34 ya\u015f\u0131ndaki bir kad\u0131n\u0131n vakas\u0131yla ba\u015flad\u0131. Kad\u0131n\u0131n t\u00fcm\u00f6rleri, imm\u00fcnoterapi ve cerrahi operasyonlara ra\u011fmen tekrar tekrar ortaya \u00e7\u0131k\u0131yordu.<\/p>\n


\n\tGenetik analiz sonucunda, t\u00fcm\u00f6r dokusunda beta-HPV\u2019nin DNA\u2019ya entegre oldu\u011fu ve vir\u00fcs\u00fcn kanserli h\u00fccrelerde t\u00fcm\u00f6r\u00fcn b\u00fcy\u00fcmesini destekleyen proteinler \u00fcretti\u011fi belirlendi. Bu bulgu, beta-HPV\u2019nin ilk kez insan h\u00fccresi DNA\u2019s\u0131na entegre oldu\u011funun g\u00f6sterilmesi a\u00e7\u0131s\u0131ndan bir ilk niteli\u011finde.<\/p>\n


\n\tKad\u0131nda ayr\u0131ca ZAP70 proteini ad\u0131 verilen bir ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccresi bile\u015fenindeki bozukluk nedeniyle, T h\u00fccrelerinin HPV\u2019ye kar\u015f\u0131 savunma olu\u015fturamad\u0131\u011f\u0131 saptand\u0131.<\/p>\n


\n\tK\u00f6k h\u00fccre nakliyle tam iyile\u015fme sa\u011fland\u0131<\/h2>\n


\n\tHastal\u0131\u011f\u0131n temel nedeninin anla\u015f\u0131lmas\u0131n\u0131n ard\u0131ndan kad\u0131na kemik ili\u011fi k\u00f6k h\u00fccre nakli yap\u0131ld\u0131. Nakil sayesinde ba\u011f\u0131\u015f\u0131kl\u0131k sistemi yenilendi ve hem cilt kanseri hem de di\u011fer HPV kaynakl\u0131 hastal\u0131klar tamamen ortadan kalkt\u0131. \u00dc\u00e7 y\u0131ll\u0131k takip s\u00fcrecinde hastal\u0131k tekrarlamad\u0131.<\/p>\n


\n\tDr. Lisco, farkl\u0131 disiplinlerden bilim insanlar\u0131n\u0131n ortak \u00e7al\u0131\u015fmas\u0131 sayesinde bu sonuca ula\u015f\u0131ld\u0131\u011f\u0131n\u0131 belirterek,<\/p>\n


\n\t\u201cBu ke\u015fif ve ba\u015far\u0131l\u0131 tedavi, viroloji, imm\u00fcnoloji, onkoloji ve transplantasyon uzmanlar\u0131n\u0131n birlikte \u00e7al\u0131\u015fmas\u0131 sayesinde m\u00fcmk\u00fcn oldu,\u201d dedi.<\/p>\n


\n\tCilt kanserine bak\u0131\u015f de\u011fi\u015febilir<\/h2>\n


\n\tAra\u015ft\u0131rmac\u0131lar, bu bulgunun ultraviyole (UV) \u0131\u015f\u0131nlar\u0131n\u0131n cilt kanserindeki rol\u00fcn\u00fc k\u00fc\u00e7\u00fcmsemedi\u011fini, ancak baz\u0131 durumlarda vir\u00fcslerin de do\u011frudan kanser nedeni olabilece\u011fini g\u00f6sterdi\u011fini vurgulad\u0131.<\/p>\n


\n\tBeta-HPV gibi genelde zarars\u0131z kabul edilen vir\u00fcslerin, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi zay\u0131f ki\u015filerde \u00f6l\u00fcmc\u00fcl sonu\u00e7lar do\u011furabilece\u011fi ifade edildi.<\/p>\n


\n\tDr. Lisco, bu bulgunun ki\u015fiye \u00f6zel tedavilerin geli\u015ftirilmesi a\u00e7\u0131s\u0131ndan \u00f6nemli bir ad\u0131m oldu\u011funu belirtti ve \u201cBu ke\u015fif, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi zay\u0131f bireylerde cSCC\u2019nin nas\u0131l geli\u015fti\u011fini ve nas\u0131l tedavi edilmesi gerekti\u011fini tamamen de\u011fi\u015ftirebilir\u201d dedi.<\/p>\n


\n\tAra\u015ft\u0131rma, New England Journal of Medicine dergisinde yay\u0131mland\u0131.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

ABD Ulusal Alerji ve Bula\u015f\u0131c\u0131 Hastal\u0131klar Enstit\u00fcs\u00fc\u2019nden (NIAID) imm\u00fcnolog Andrea Lisco liderli\u011findeki ara\u015ft\u0131rma ekibi, \u201cbeta-HPV\u201d olarak bilinen vir\u00fcs\u00fcn, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi zay\u0131flam\u0131\u015f bireylerde h\u00fccrelerin DNA\u2019s\u0131na yerle\u015ferek kanser geli\u015fimini tetikleyebildi\u011fini tespit etti. 34 ya\u015f\u0131ndaki kad\u0131n\u0131n vakas\u0131 bilimsel d\u00f6n\u00fcm noktas\u0131 oldu Ara\u015ft\u0131rma, al\u0131n b\u00f6lgesinde kutan\u00f6z skuam\u00f6z h\u00fccreli karsinom (cSCC) ad\u0131 verilen bir t\u00fcr cilt kanseri […]<\/p>\n","protected":false},"author":1,"featured_media":31613,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[2],"tags":[],"class_list":["post-31612","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"yoast_head":"\nBilim insanlar\u0131 yayg\u0131n bir kanser t\u00fcr\u00fcn\u00fcn viral nedenini ke\u015ffetti - Haber Kuzey<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/haberkuzey.com\/index.php\/2025\/11\/12\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bilim insanlar\u0131 yayg\u0131n bir kanser t\u00fcr\u00fcn\u00fcn viral nedenini ke\u015ffetti - Haber Kuzey\" \/>\n<meta property=\"og:description\" content=\" ABD Ulusal Alerji ve Bula\u015f\u0131c\u0131 Hastal\u0131klar Enstit\u00fcs\u00fc\u2019nden (NIAID) imm\u00fcnolog Andrea Lisco liderli\u011findeki ara\u015ft\u0131rma ekibi, \u201cbeta-HPV\u201d olarak bilinen vir\u00fcs\u00fcn, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi zay\u0131flam\u0131\u015f bireylerde h\u00fccrelerin DNA\u2019s\u0131na yerle\u015ferek kanser geli\u015fimini tetikleyebildi\u011fini tespit etti. 34 ya\u015f\u0131ndaki kad\u0131n\u0131n vakas\u0131 bilimsel d\u00f6n\u00fcm noktas\u0131 oldu Ara\u015ft\u0131rma, al\u0131n b\u00f6lgesinde kutan\u00f6z skuam\u00f6z h\u00fccreli karsinom (cSCC) ad\u0131 verilen bir t\u00fcr cilt kanseri […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/haberkuzey.com\/index.php\/2025\/11\/12\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\/\" \/>\n<meta property=\"og:site_name\" content=\"Haber Kuzey\" \/>\n<meta property=\"article:published_time\" content=\"2025-11-12T02:30:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trthaberstatic.cdn.wp.trt.com.tr\/resimler\/2248000\/cilt-kanseri-muayene-2248984.jpg\" \/>\n<meta name=\"author\" content=\"haberkuzey\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"haberkuzey\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/11\\\/12\\\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/11\\\/12\\\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\\\/\"},\"author\":{\"name\":\"haberkuzey\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/#\\\/schema\\\/person\\\/3372109ec735f9333f4fa47ebb9605ca\"},\"headline\":\"Bilim insanlar\u0131 yayg\u0131n bir kanser t\u00fcr\u00fcn\u00fcn viral nedenini ke\u015ffetti\",\"datePublished\":\"2025-11-12T02:30:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/11\\\/12\\\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\\\/\"},\"wordCount\":447,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/11\\\/12\\\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/haberkuzey.com\\\/wp-content\\\/uploads\\\/2025\\\/11\\\/cilt-kanseri-muayene-2248984.jpg\",\"articleSection\":[\"D\u00fcnya\"],\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/11\\\/12\\\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/11\\\/12\\\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\\\/\",\"url\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/11\\\/12\\\/bilim-insanlari-yaygin-bir-kanser-turunun-viral-nedenini-kesfetti\\\/\",\"name\":\"Bilim insanlar\u0131 yayg\u0131n bir kanser t\u00fcr\u00fcn\u00fcn viral nedenini ke\u015ffetti - 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