\n
\n\tMetastatik pankreas kanseri olan 83 hasta \u00fczerinde yap\u0131lan ilk denemede, hastalar\u0131n y\u00fczde 29\u2019unda t\u00fcm\u00f6rlerde k\u00fc\u00e7\u00fclme, y\u00fczde 90\u2019\u0131nda ise yeni t\u00fcm\u00f6r geli\u015fiminin durdu\u011fu g\u00f6zlendi.<\/p>\n
\n\tOrtalama sa\u011fkal\u0131m s\u00fcresi 15,6 aya \u00e7\u0131kt\u0131. Bu s\u00fcre, hastal\u0131\u011f\u0131n beklenen ya\u015fam s\u00fcresinin yakla\u015f\u0131k iki kat\u0131.<\/p>\n
\n\tBir hastada t\u00fcm\u00f6r\u00fcn tedaviye ba\u015flad\u0131ktan sonra y\u00fczde 64 oran\u0131nda k\u00fc\u00e7\u00fcld\u00fc\u011f\u00fc bildirildi. Washington Post\u2019a konu\u015fan 69 ya\u015f\u0131ndaki hasta Debbie Orcutt, \u201cZaten kaybedecek bir \u015feyim yoktu. Denemeye karar verdim\u201d dedi.<\/p>\n
\n\tTrump y\u00f6netiminden h\u0131zl\u0131 onay program\u0131<\/h2>\n
\n\tFDA, Ekim ay\u0131nda Revolution Medicines\u2019in ilac\u0131na \u201cCommissioner\u2019s National Priority Voucher\u201d kapsam\u0131nda h\u0131zland\u0131r\u0131lm\u0131\u015f de\u011ferlendirme hakk\u0131 tan\u0131d\u0131. Bu sistem, de\u011ferlendirme s\u00fcresini bir y\u0131ldan bir aya kadar indirebiliyor.<\/p>\n
\n\tAyn\u0131 program kapsam\u0131nda do\u011furganl\u0131k, tip 1 diyabet, i\u015fitme kayb\u0131, k\u00f6rl\u00fck, ba\u011f\u0131ml\u0131l\u0131k ve nadir kan hastal\u0131klar\u0131na y\u00f6nelik baz\u0131 ila\u00e7lar da \u00f6ncelikli inceleme hakk\u0131 kazand\u0131.<\/p>\n
\n\tABD Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131 s\u00f6zc\u00fcs\u00fc Andrew Nixon, s\u00fcre\u00e7lerin \u201cbilimsel titizlikten \u00f6d\u00fcn verilmeden\u201d h\u0131zland\u0131r\u0131laca\u011f\u0131n\u0131 s\u00f6yledi.<\/p>\n
\n\tKanser ara\u015ft\u0131rmalar\u0131nda d\u00f6n\u00fcm noktas\u0131<\/h2>\n
\n\tDaraxonrasib, RAS gen ailesindeki mutasyonlar\u0131 hedef al\u0131yor. Bu genler h\u00fccre b\u00fcy\u00fcmesini kontrol eden \u201ca\u00e7-kapa\u201d anahtarlar\u0131 gibi \u00e7al\u0131\u015f\u0131yor; ancak mutasyona u\u011frad\u0131klar\u0131nda h\u00fccreler kontrols\u00fcz \u00e7o\u011falabiliyor.<\/p>\n
\n\tRevolution Medicines\u2019in kurucular\u0131ndan Prof. Kevan Shokat, 2013\u2019te bu genlerin yol a\u00e7t\u0131\u011f\u0131 sinyal bozukluklar\u0131n\u0131 durdurabilecek yeni bir mekanizma geli\u015ftirdi. \u015eirket daha sonra bu y\u00f6ntemi farkl\u0131 proteinlere uyarlad\u0131.<\/p>\n
\n\t\u015eirket CEO\u2019su Mark Goldsmith, \u201c\u00c7o\u011fu bilim insan\u0131 y\u00f6ntemin sa\u011fl\u0131kl\u0131 h\u00fccreleri de yok edece\u011fini d\u00fc\u015f\u00fcn\u00fcyordu, ama hayvan deneylerinde toksik etki g\u00f6r\u00fclmedi,\u201d dedi.<\/p>\n
\n\tEtkileyici ama s\u0131n\u0131rl\u0131 sonu\u00e7lar<\/h2>\n
\n\tDaraxonrasib, baz\u0131 hastalarda ya\u015fam s\u00fcresini uzatsa da hen\u00fcz kesin bir tedavi olarak g\u00f6r\u00fclm\u00fcyor. 40 hasta \u00fczerinde yap\u0131lan bir ba\u015fka \u00e7al\u0131\u015fmada kat\u0131l\u0131mc\u0131lar\u0131n y\u00fczde 95\u2019i yan etki, y\u00fczde 35\u2019i ise ciddi yan etki ya\u015fad\u0131.<\/p>\n
\n\tDana-Farber Kanser Enstit\u00fcs\u00fc\u2019nden Dr. Brian Wolpin, \u201cBu ila\u00e7, pankreas kanseri ara\u015ft\u0131rmalar\u0131nda bir d\u00f6n\u00fcm noktas\u0131 olabilir,\u201d diyerek tedavinin t\u00fcm\u00f6rleri k\u00fc\u00e7\u00fclt\u00fcp hastalar\u0131n a\u011fr\u0131s\u0131n\u0131 hafifletti\u011fini belirtti.<\/p>\n
\n\tEn \u00f6l\u00fcmc\u00fcl kanser t\u00fcrlerinden biri<\/h2>\n
\n\tPankreas kanseri, ABD\u2019de kanser kaynakl\u0131 \u00f6l\u00fcmlerin \u00fc\u00e7\u00fcnc\u00fc nedeni. Hastalar\u0131n yaln\u0131zca y\u00fczde 13\u2019\u00fc be\u015f y\u0131ldan fazla ya\u015fayabiliyor. Metastaz durumunda bu oran y\u00fczde 3\u2019e kadar d\u00fc\u015f\u00fcyor.<\/p>\n
\n\tPancreatic Cancer Action Network Ba\u015fkan\u0131 Anna Berkenblit, daraxonrasib\u2019in h\u0131zl\u0131 onay almas\u0131n\u0131 memnuniyetle kar\u015f\u0131lad\u0131:<\/p>\n
\n\t\u201cRAS mutasyonlar\u0131n\u0131 hedef alan bu ila\u00e7, pankreas kanseri tedavisinde ger\u00e7ek bir s\u0131\u00e7rama anlam\u0131na geliyor.\u201d<\/p>\n
\n\tDeneysel tedavilerde umut<\/h2>\n
\n\t55 ya\u015f\u0131ndaki molek\u00fcler biyolog Pranati Perati, 2023\u2019te ilac\u0131 almaya ba\u015flad\u0131\u011f\u0131nda di\u011fer tedavilere yan\u0131t vermemi\u015fti. \u0130lac\u0131n iki y\u0131l boyunca t\u00fcm\u00f6rlerin yay\u0131lmas\u0131n\u0131 durdurdu\u011funu ve ona \u201cekstra ya\u015fam s\u00fcresi\u201d kazand\u0131rd\u0131\u011f\u0131n\u0131 anlatt\u0131.<\/p>\n
\n\tFDA\u2019n\u0131n h\u0131zland\u0131r\u0131lm\u0131\u015f onay sisteminin, yeni kanser ila\u00e7lar\u0131n\u0131 daha erken eri\u015filebilir k\u0131labilece\u011fi d\u00fc\u015f\u00fcn\u00fcl\u00fcyor.<\/p>\n
\n\tAncak uzmanlar, bu h\u0131z\u0131n bilimsel do\u011frulama s\u00fcre\u00e7lerini zay\u0131flatmamas\u0131 gerekti\u011fi konusunda hemfikir.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"
Metastatik pankreas kanseri olan 83 hasta \u00fczerinde yap\u0131lan ilk denemede, hastalar\u0131n y\u00fczde 29\u2019unda t\u00fcm\u00f6rlerde k\u00fc\u00e7\u00fclme, y\u00fczde 90\u2019\u0131nda ise yeni t\u00fcm\u00f6r geli\u015fiminin durdu\u011fu g\u00f6zlendi.
Ortalama sa\u011fkal\u0131m s\u00fcresi 15,6 aya \u00e7\u0131kt\u0131. Bu s\u00fcre, hastal\u0131\u011f\u0131n beklenen ya\u015fam s\u00fcresinin yakla\u015f\u0131k iki kat\u0131.
Bir hastada t\u00fcm\u00f6r\u00fcn tedaviye ba\u015flad\u0131ktan sonra y\u00fczde 64 oran\u0131nda k\u00fc\u00e7\u00fcld\u00fc\u011f\u00fc bildirildi. Washington Post\u2019a konu\u015fan […]<\/p>\n","protected":false},"author":1,"featured_media":31411,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[2],"tags":[],"class_list":["post-31410","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"yoast_head":"\n
Devrim niteli\u011findeki ila\u00e7 en \u00f6l\u00fcmc\u00fcl kanser t\u00fcrlerinden birinde umut vadediyor - Haber Kuzey<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/haberkuzey.com\/index.php\/2025\/11\/06\/devrim-niteligindeki-ilac-en-olumcul-kanser-turlerinden-birinde-umut-vadediyor\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Devrim niteli\u011findeki ila\u00e7 en \u00f6l\u00fcmc\u00fcl kanser t\u00fcrlerinden birinde umut vadediyor - Haber Kuzey\" \/>\n<meta property=\"og:description\" content=\"
Metastatik pankreas kanseri olan 83 hasta \u00fczerinde yap\u0131lan ilk denemede, hastalar\u0131n y\u00fczde 29\u2019unda t\u00fcm\u00f6rlerde k\u00fc\u00e7\u00fclme, y\u00fczde 90\u2019\u0131nda ise yeni t\u00fcm\u00f6r geli\u015fiminin durdu\u011fu g\u00f6zlendi.
Ortalama sa\u011fkal\u0131m s\u00fcresi 15,6 aya \u00e7\u0131kt\u0131. Bu s\u00fcre, hastal\u0131\u011f\u0131n beklenen ya\u015fam s\u00fcresinin yakla\u015f\u0131k iki kat\u0131.
Bir hastada t\u00fcm\u00f6r\u00fcn tedaviye ba\u015flad\u0131ktan sonra y\u00fczde 64 oran\u0131nda k\u00fc\u00e7\u00fcld\u00fc\u011f\u00fc bildirildi. 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Haber Kuzey","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/haberkuzey.com\/index.php\/2025\/11\/06\/devrim-niteligindeki-ilac-en-olumcul-kanser-turlerinden-birinde-umut-vadediyor\/","og_locale":"tr_TR","og_type":"article","og_title":"Devrim niteli\u011findeki ila\u00e7 en \u00f6l\u00fcmc\u00fcl kanser t\u00fcrlerinden birinde umut vadediyor - Haber Kuzey","og_description":"
Metastatik pankreas kanseri olan 83 hasta \u00fczerinde yap\u0131lan ilk denemede, hastalar\u0131n y\u00fczde 29\u2019unda t\u00fcm\u00f6rlerde k\u00fc\u00e7\u00fclme, y\u00fczde 90\u2019\u0131nda ise yeni t\u00fcm\u00f6r geli\u015fiminin durdu\u011fu g\u00f6zlendi.
Ortalama sa\u011fkal\u0131m s\u00fcresi 15,6 aya \u00e7\u0131kt\u0131. Bu s\u00fcre, hastal\u0131\u011f\u0131n beklenen ya\u015fam s\u00fcresinin yakla\u015f\u0131k iki kat\u0131.
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