\n
\n\tNormal ko\u015fullarda, b\u00f6brek nakillerinde don\u00f6r ve al\u0131c\u0131 kan gruplar\u0131n\u0131n uyumlu olmas\u0131 gerekiyor. \u00d6zellikle O grubu hastalar, yaln\u0131zca O grubu b\u00f6brek alabiliyor. Bu da d\u00fcnya genelinde nakil listelerinin yar\u0131s\u0131ndan fazlas\u0131n\u0131 olu\u015fturan O grubu hastalar i\u00e7in bekleme s\u00fcresini dramatik bi\u00e7imde uzat\u0131yor.<\/p>\n
\n\tAra\u015ft\u0131rmac\u0131lar bu sorunu a\u015fmak i\u00e7in, A grubu b\u00f6bre\u011fi \u201cO grubu b\u00f6bre\u011fe d\u00f6n\u00fc\u015ft\u00fcrmeyi\u201d ba\u015fard\u0131. \u00c7al\u0131\u015fmada, kan grubunu belirleyen \u015feker molek\u00fcllerini (antijenleri) b\u00f6brekten \u201ckesip atan\u201d \u00f6zel enzimler kullan\u0131ld\u0131.<\/p>\n
\n\tAra\u015ft\u0131rman\u0131n ba\u015fyazar\u0131, Kanada\u2019daki British Columbia \u00dcniversitesi\u2019nden Biyokimyager Stephen Withers, \u201cBu enzimleri molek\u00fcler makas gibi kullan\u0131yoruz. Kan grubu antijenlerini temizledi\u011fimizde, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi organ\u0131 art\u0131k yabanc\u0131 olarak g\u00f6rm\u00fcyor\u201d dedi.<\/p>\n
\n\t\u0130lk kez insan modeli \u00fczerinde denendi<\/h2>\n
\n\tAra\u015ft\u0131rma ekibi, d\u00f6n\u00fc\u015ft\u00fcr\u00fclm\u00fc\u015f b\u00f6bre\u011fi beyin \u00f6l\u00fcm\u00fc ger\u00e7ekle\u015fmi\u015f bir insanda k\u0131sa s\u00fcreli test etti. B\u00f6brek birka\u00e7 g\u00fcn boyunca \u00e7al\u0131\u015fmaya ve idrar \u00fcretmeye devam etti. Ancak \u00fc\u00e7\u00fcnc\u00fc g\u00fcn, kan dola\u015f\u0131m\u0131nda yeniden A tipi molek\u00fcller g\u00f6r\u00fclmeye ba\u015flad\u0131 ve hafif bir ba\u011f\u0131\u015f\u0131kl\u0131k tepkisi olu\u015ftu.<\/p>\n
\n\tWithers, \u201cBu tepki beklenenden \u00e7ok daha zay\u0131ft\u0131. V\u00fccut, b\u00f6bre\u011fi tolere etmeye \u00e7al\u0131\u015f\u0131yordu. Bu, uzun vadede umut verici bir sinyal,\u201d dedi.<\/p>\n
\n\tNakil bekleyen binlerce ki\u015fi i\u00e7in umut<\/h2>\n
\n\tABD\u2019de her g\u00fcn ortalama 11 ki\u015fi b\u00f6brek nakli beklerken hayat\u0131n\u0131 kaybediyor. \u00c7al\u0131\u015fman\u0131n ara\u015ft\u0131rmac\u0131lar\u0131na g\u00f6re bu y\u00f6ntem geli\u015ftirilirse, kan grubu uyumsuzlu\u011fu nedeniyle organ bekleyen binlerce hastan\u0131n hayat\u0131 kurtar\u0131labilir.<\/p>\n
\n\t\u00d6n\u00fcm\u00fczdeki ad\u0131mlar<\/h2>\n
\n\tBilim insanlar\u0131 \u015fimdi y\u00f6ntemin uzun vadeli dayan\u0131kl\u0131l\u0131\u011f\u0131n\u0131 ve g\u00fcvenli\u011fini test etmeyi planl\u0131yor. Canl\u0131 insan denemelerine ge\u00e7ilmeden \u00f6nce, b\u00f6bre\u011fin ba\u011f\u0131\u015f\u0131kl\u0131k tepkilerine kar\u015f\u0131 tam koruma sa\u011flayacak enzim kombinasyonlar\u0131 \u00fczerinde \u00e7al\u0131\u015f\u0131l\u0131yor.<\/p>\n
\n\tAra\u015ft\u0131rman\u0131n sonu\u00e7lar\u0131, Nature Biomedical Engineering dergisinde yay\u0131mland\u0131.<\/p>\n
\n\tWithers, \u201cBu, temel bilimin hasta bak\u0131m\u0131na dokundu\u011fu anlardan biri. Y\u0131llar s\u00fcren laboratuvar \u00e7al\u0131\u015fmalar\u0131n\u0131n, ger\u00e7ek hayat kurtarmaya yakla\u015ft\u0131\u011f\u0131n\u0131 g\u00f6rmek bizi motive ediyor\u201d dedi.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"
Normal ko\u015fullarda, b\u00f6brek nakillerinde don\u00f6r ve al\u0131c\u0131 kan gruplar\u0131n\u0131n uyumlu olmas\u0131 gerekiyor. \u00d6zellikle O grubu hastalar, yaln\u0131zca O grubu b\u00f6brek alabiliyor. Bu da d\u00fcnya genelinde nakil listelerinin yar\u0131s\u0131ndan fazlas\u0131n\u0131 olu\u015fturan O grubu hastalar i\u00e7in bekleme s\u00fcresini dramatik bi\u00e7imde uzat\u0131yor.
Ara\u015ft\u0131rmac\u0131lar bu sorunu a\u015fmak i\u00e7in, A grubu b\u00f6bre\u011fi \u201cO grubu b\u00f6bre\u011fe d\u00f6n\u00fc\u015ft\u00fcrmeyi\u201d ba\u015fard\u0131. \u00c7al\u0131\u015fmada, […]<\/p>\n","protected":false},"author":1,"featured_media":30161,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[2],"tags":[],"class_list":["post-30160","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"yoast_head":"\n
\u00c7\u0131\u011f\u0131r a\u00e7an geli\u015fme: Her kan grubuna uyumlu evrensel b\u00f6brek geli\u015ftirildi - Haber Kuzey<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00c7\u0131\u011f\u0131r a\u00e7an geli\u015fme: Her kan grubuna uyumlu evrensel b\u00f6brek geli\u015ftirildi - Haber Kuzey\" \/>\n<meta property=\"og:description\" content=\"
Normal ko\u015fullarda, b\u00f6brek nakillerinde don\u00f6r ve al\u0131c\u0131 kan gruplar\u0131n\u0131n uyumlu olmas\u0131 gerekiyor. \u00d6zellikle O grubu hastalar, yaln\u0131zca O grubu b\u00f6brek alabiliyor. Bu da d\u00fcnya genelinde nakil listelerinin yar\u0131s\u0131ndan fazlas\u0131n\u0131 olu\u015fturan O grubu hastalar i\u00e7in bekleme s\u00fcresini dramatik bi\u00e7imde uzat\u0131yor.
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Haber Kuzey","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/","og_locale":"tr_TR","og_type":"article","og_title":"\u00c7\u0131\u011f\u0131r a\u00e7an geli\u015fme: Her kan grubuna uyumlu evrensel b\u00f6brek geli\u015ftirildi - Haber Kuzey","og_description":"
Normal ko\u015fullarda, b\u00f6brek nakillerinde don\u00f6r ve al\u0131c\u0131 kan gruplar\u0131n\u0131n uyumlu olmas\u0131 gerekiyor. \u00d6zellikle O grubu hastalar, yaln\u0131zca O grubu b\u00f6brek alabiliyor. Bu da d\u00fcnya genelinde nakil listelerinin yar\u0131s\u0131ndan fazlas\u0131n\u0131 olu\u015fturan O grubu hastalar i\u00e7in bekleme s\u00fcresini dramatik bi\u00e7imde uzat\u0131yor.
Ara\u015ft\u0131rmac\u0131lar bu sorunu a\u015fmak i\u00e7in, A grubu b\u00f6bre\u011fi \u201cO grubu b\u00f6bre\u011fe d\u00f6n\u00fc\u015ft\u00fcrmeyi\u201d ba\u015fard\u0131. \u00c7al\u0131\u015fmada, […]","og_url":"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/","og_site_name":"Haber Kuzey","article_published_time":"2025-10-16T06:36:41+00:00","og_image":[{"url":"https:\/\/trthaberstatic.cdn.wp.trt.com.tr\/resimler\/2062000\/dunyanin-en-buyuk-bsobrek-tasi-sri-lanka-ordusu-2062977.jpg","type":"","width":"","height":""}],"author":"haberkuzey","twitter_card":"summary_large_image","twitter_misc":{"Yazan:":"haberkuzey","Tahmini okuma s\u00fcresi":"2 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/#article","isPartOf":{"@id":"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/"},"author":{"name":"haberkuzey","@id":"https:\/\/haberkuzey.com\/#\/schema\/person\/3372109ec735f9333f4fa47ebb9605ca"},"headline":"\u00c7\u0131\u011f\u0131r a\u00e7an geli\u015fme: Her kan grubuna uyumlu evrensel b\u00f6brek geli\u015ftirildi","datePublished":"2025-10-16T06:36:41+00:00","mainEntityOfPage":{"@id":"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/"},"wordCount":396,"commentCount":0,"image":{"@id":"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/#primaryimage"},"thumbnailUrl":"https:\/\/haberkuzey.com\/wp-content\/uploads\/2025\/10\/dunyanin-en-buyuk-bsobrek-tasi-sri-lanka-ordusu-2062977.jpg","articleSection":["D\u00fcnya"],"inLanguage":"tr","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/","url":"https:\/\/haberkuzey.com\/index.php\/2025\/10\/16\/cigir-acan-gelisme-her-kan-grubuna-uyumlu-evrensel-bobrek-gelistirildi\/","name":"\u00c7\u0131\u011f\u0131r a\u00e7an geli\u015fme: Her kan grubuna uyumlu evrensel b\u00f6brek geli\u015ftirildi - 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