{"id":29639,"date":"2025-09-25T21:41:59","date_gmt":"2025-09-25T18:41:59","guid":{"rendered":"https:\/\/haberkuzey.com\/index.php\/2025\/09\/25\/tedavisi-olmayan-huntington-hastaliginda-ilk-kez-tedavi-gelistirildi\/"},"modified":"2025-09-25T21:41:59","modified_gmt":"2025-09-25T18:41:59","slug":"tedavisi-olmayan-huntington-hastaliginda-ilk-kez-tedavi-gelistirildi","status":"publish","type":"post","link":"https:\/\/haberkuzey.com\/index.php\/2025\/09\/25\/tedavisi-olmayan-huntington-hastaliginda-ilk-kez-tedavi-gelistirildi\/","title":{"rendered":"Tedavisi olmayan Huntington hastal\u0131\u011f\u0131nda ilk kez tedavi geli\u015ftirildi"},"content":{"rendered":"<p><\/p>\n<div>\n<p>&#13;<br \/>\n\tHuntington hastal\u0131\u011f\u0131 hareket, d\u00fc\u015f\u00fcnce ve duygu durumunu etkileyen, kal\u0131tsal ve tedavisi bulunmayan bir beyin bozuklu\u011fu olarak biliniyor.<\/p>\n<p>&#13;<br \/>\n\tErken evre klinik \u00e7al\u0131\u015fmaya kat\u0131lan 29 hastadan y\u00fcksek doz alanlarda 36 ay sonunda hastal\u0131\u011f\u0131n ilerleyi\u015finde y\u00fczde 75 oran\u0131nda yava\u015flama g\u00f6r\u00fcld\u00fc.<\/p>\n<p>&#13;<br \/>\n\tTedaviyi geli\u015ftiren Hollanda ve ABD merkezli gen tedavisi \u015firketi uniQure, AMT-130 adl\u0131 gen terapisinin tek doz halinde uygulanmas\u0131n\u0131n bir \u00f6m\u00fcr boyu etkili olabilece\u011fini a\u00e7\u0131klad\u0131.<\/p>\n<h2>&#13;<br \/>\n\t\u201cBu sonu\u00e7 her \u015feyi de\u011fi\u015ftiriyor\u201d<\/h2>\n<p>&#13;<br \/>\n\t\u00c7al\u0131\u015fman\u0131n ba\u015f ara\u015ft\u0131rmac\u0131s\u0131 Prof. Ed Wild, \u201cBu sonu\u00e7, Huntington hastal\u0131\u011f\u0131nda ilk kez hastal\u0131\u011f\u0131n seyrini de\u011fi\u015ftiren bir tedaviye ula\u015ft\u0131\u011f\u0131m\u0131z\u0131 g\u00f6steriyor.<\/p>\n<p>&#13;<br \/>\n\tAMT-130\u2019un onay almas\u0131 halinde bu, d\u00fcnya \u00e7ap\u0131nda d\u00f6n\u00fcm noktas\u0131 olacak\u201d dedi. Prof. Wild, deneklerin b\u00fcy\u00fck bir cesaret g\u00f6stererek beyin ameliyat\u0131na girdi\u011fini ve tedaviyi alan baz\u0131 hastalar\u0131n\u0131n uzun s\u00fcre stabil kald\u0131\u011f\u0131n\u0131, hatta emeklilikten i\u015fe geri d\u00f6nen bir hasta oldu\u011funu vurgulad\u0131.<\/p>\n<h2>&#13;<br \/>\n\tG\u00fcnl\u00fck ya\u015fam fonksiyonlar\u0131 korunabilecek<\/h2>\n<p>&#13;<br \/>\n\tUCL\u2019den Prof. Sarah Tabrizi ise, \u201cBu \u00e7al\u0131\u015fma, 36 ay sonunda istatistiksel olarak anlaml\u0131 sonu\u00e7lar ortaya koydu. Huntington hastal\u0131\u011f\u0131nda ilk kez bu kadar g\u00fc\u00e7l\u00fc kan\u0131t g\u00f6r\u00fcyoruz. AMT-130, hastalar\u0131n g\u00fcnl\u00fck fonksiyonlar\u0131n\u0131 korumas\u0131na, i\u015f hayat\u0131nda daha uzun s\u00fcre kalmas\u0131na ve hastal\u0131\u011f\u0131n ilerlemesini anlaml\u0131 \u00f6l\u00e7\u00fcde yava\u015flatmas\u0131na imkan tan\u0131yabilir\u201d ifadelerini kulland\u0131.<\/p>\n<p>&#13;<br \/>\n\tUzmanlar, bu tedavinin ruhsat almas\u0131 halinde Huntington hastal\u0131\u011f\u0131nda \u00e7\u0131\u011f\u0131r a\u00e7aca\u011f\u0131n\u0131 ve hastalara umut olaca\u011f\u0131n\u0131 belirtiyor.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>&#13; Huntington hastal\u0131\u011f\u0131 hareket, d\u00fc\u015f\u00fcnce ve duygu durumunu etkileyen, kal\u0131tsal ve tedavisi bulunmayan bir beyin bozuklu\u011fu olarak biliniyor. &#13; Erken evre klinik \u00e7al\u0131\u015fmaya kat\u0131lan 29 hastadan y\u00fcksek doz alanlarda 36 ay sonunda hastal\u0131\u011f\u0131n ilerleyi\u015finde y\u00fczde 75 oran\u0131nda yava\u015flama g\u00f6r\u00fcld\u00fc. &#13; Tedaviyi geli\u015ftiren Hollanda ve ABD merkezli gen tedavisi \u015firketi uniQure, AMT-130 adl\u0131 gen terapisinin tek [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":29640,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[2],"tags":[],"class_list":["post-29639","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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