{"id":29377,"date":"2025-09-16T14:44:20","date_gmt":"2025-09-16T11:44:20","guid":{"rendered":"https:\/\/haberkuzey.com\/index.php\/2025\/09\/16\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\/"},"modified":"2025-09-16T14:44:20","modified_gmt":"2025-09-16T11:44:20","slug":"uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir","status":"publish","type":"post","link":"https:\/\/haberkuzey.com\/index.php\/2025\/09\/16\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\/","title":{"rendered":"Uykusuzluk, beyinde tehlikeli toksinlerin birikmesine yol a\u00e7abilir"},"content":{"rendered":"<p><\/p>\n<div>\n<p>&#13;<br \/>\n\tV\u00fccuttaki h\u00fccreler at\u0131k \u00fcretir ve bu at\u0131klar lenf sistemiyle temizlenir. Ancak beynin lenf damarlar\u0131 yoktur. Yakla\u015f\u0131k 12 y\u0131l \u00f6nce ke\u015ffedilen glimfatik sistem, beyin-omurilik s\u0131v\u0131s\u0131n\u0131 kullanarak h\u00fccreler aras\u0131ndaki at\u0131klar\u0131 toplar ve toplardamarlara aktar\u0131r.<\/p>\n<p>&#13;<br \/>\n\tFareler \u00fczerinde yap\u0131lan \u00e7al\u0131\u015fmalar, bu sistemin uykuda \u00e7ok daha aktif oldu\u011funu ve \u00f6zellikle Alzheimer hastal\u0131\u011f\u0131nda rol oynayan beta amiloid proteinlerini temizledi\u011fini g\u00f6stermi\u015ftir. \u0130nsanlarda da uykusuz ge\u00e7en tek bir geceden sonra beyinde seviyelerinin artt\u0131\u011f\u0131 g\u00f6zlenmi\u015ftir.<\/p>\n<h2>&#13;<br \/>\n\tUyku bozukluklar\u0131 ve risk<\/h2>\n<p>&#13;<br \/>\n\tUyku apnesi: Uykuda solunumun s\u0131k s\u0131k durmas\u0131 nedeniyle hem oksijen d\u00fc\u015fer hem de uyku b\u00f6l\u00fcn\u00fcr. Bu durum, beyinde toksin birikimine ve demans riskine yol a\u00e7abilir. Tedavi edilen hastalarda A\u03b2 temizlenmesinin artt\u0131\u011f\u0131 g\u00f6sterilmi\u015ftir.<\/p>\n<p>&#13;<br \/>\n\t\u0130nsomnia (uykusuzluk): Uzun vadede Alzheimer riskini art\u0131r\u0131r, ancak tedavisinin toksin temizli\u011fi \u00fczerindeki etkisi hen\u00fcz bilinmiyor.<\/p>\n<h2>&#13;<br \/>\n\tDaha \u00e7ok ara\u015ft\u0131rmaya ihtiya\u00e7 var<\/h2>\n<p>&#13;<br \/>\n\tUzmanlara g\u00f6re kaliteli uyku, beyin sa\u011fl\u0131\u011f\u0131 i\u00e7in kritik \u00f6neme sahip. Ancak tedaviyle toksinlerin temizlenmesinin do\u011frudan demans riskini d\u00fc\u015f\u00fcr\u00fcp d\u00fc\u015f\u00fcrmedi\u011fi hen\u00fcz kesinle\u015fmedi.<\/p>\n<p>&#13;<br \/>\n\tAra\u015ft\u0131rmalar, \u00f6zellikle A\u03b2 ve tau proteinlerinin kan d\u00fczeylerini uyku-uyan\u0131kl\u0131k d\u00f6ng\u00fcs\u00fc boyunca izleyerek, uyku apnesi ve insomnia tedavisinin beyin temizli\u011fi \u00fczerindeki etkisini anlamaya odaklan\u0131yor.<\/p>\n<h2>&#13;<br \/>\n\tUzmanlar\u0131n \u00f6nerisi<\/h2>\n<p>&#13;<br \/>\n\tBeyin sa\u011fl\u0131\u011f\u0131 ve bili\u015fsel i\u015flevler konusunda endi\u015fe ya\u015fayanlar\u0131n, uyku d\u00fczenlerini takip etmeleri ve bir hekime ba\u015fvurmalar\u0131 tavsiye ediliyor.<\/p>\n<p>&#13;<br \/>\n\tBu \u00e7al\u0131\u015fma The Conversation i\u00e7in kaleme al\u0131nan makaleden uyarland\u0131.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>&#13; V\u00fccuttaki h\u00fccreler at\u0131k \u00fcretir ve bu at\u0131klar lenf sistemiyle temizlenir. Ancak beynin lenf damarlar\u0131 yoktur. Yakla\u015f\u0131k 12 y\u0131l \u00f6nce ke\u015ffedilen glimfatik sistem, beyin-omurilik s\u0131v\u0131s\u0131n\u0131 kullanarak h\u00fccreler aras\u0131ndaki at\u0131klar\u0131 toplar ve toplardamarlara aktar\u0131r. &#13; Fareler \u00fczerinde yap\u0131lan \u00e7al\u0131\u015fmalar, bu sistemin uykuda \u00e7ok daha aktif oldu\u011funu ve \u00f6zellikle Alzheimer hastal\u0131\u011f\u0131nda rol oynayan beta amiloid proteinlerini temizledi\u011fini [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":29378,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[2],"tags":[],"class_list":["post-29377","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dunya"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Uykusuzluk, beyinde tehlikeli toksinlerin birikmesine yol a\u00e7abilir - Haber Kuzey<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/haberkuzey.com\/index.php\/2025\/09\/16\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Uykusuzluk, beyinde tehlikeli toksinlerin birikmesine yol a\u00e7abilir - Haber Kuzey\" \/>\n<meta property=\"og:description\" content=\"&#013; V\u00fccuttaki h\u00fccreler at\u0131k \u00fcretir ve bu at\u0131klar lenf sistemiyle temizlenir. 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Yakla\u015f\u0131k 12 y\u0131l \u00f6nce ke\u015ffedilen glimfatik sistem, beyin-omurilik s\u0131v\u0131s\u0131n\u0131 kullanarak h\u00fccreler aras\u0131ndaki at\u0131klar\u0131 toplar ve toplardamarlara aktar\u0131r. &#013; Fareler \u00fczerinde yap\u0131lan \u00e7al\u0131\u015fmalar, bu sistemin uykuda \u00e7ok daha aktif oldu\u011funu ve \u00f6zellikle Alzheimer hastal\u0131\u011f\u0131nda rol oynayan beta amiloid proteinlerini temizledi\u011fini [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/haberkuzey.com\/index.php\/2025\/09\/16\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\/\" \/>\n<meta property=\"og:site_name\" content=\"Haber Kuzey\" \/>\n<meta property=\"article:published_time\" content=\"2025-09-16T11:44:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/trthaberstatic.cdn.wp.trt.com.tr\/resimler\/2366000\/uykusuzluk-getty-2367157.jpg\" \/>\n<meta name=\"author\" content=\"haberkuzey\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"haberkuzey\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/09\\\/16\\\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/09\\\/16\\\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\\\/\"},\"author\":{\"name\":\"haberkuzey\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/#\\\/schema\\\/person\\\/3372109ec735f9333f4fa47ebb9605ca\"},\"headline\":\"Uykusuzluk, beyinde tehlikeli toksinlerin birikmesine yol a\u00e7abilir\",\"datePublished\":\"2025-09-16T11:44:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/09\\\/16\\\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\\\/\"},\"wordCount\":272,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/09\\\/16\\\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/haberkuzey.com\\\/wp-content\\\/uploads\\\/2025\\\/09\\\/uykusuzluk-getty-2367157.jpg\",\"articleSection\":[\"D\u00fcnya\"],\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/09\\\/16\\\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/09\\\/16\\\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\\\/\",\"url\":\"https:\\\/\\\/haberkuzey.com\\\/index.php\\\/2025\\\/09\\\/16\\\/uykusuzluk-beyinde-tehlikeli-toksinlerin-birikmesine-yol-acabilir\\\/\",\"name\":\"Uykusuzluk, beyinde tehlikeli toksinlerin birikmesine yol a\u00e7abilir - 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